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Preeclampsia and risk of developing subsequent diabetes
D B Carr1, K M Newton, K M Utzschneider
1Department of Obstetrics & Gynecology, University of Washington, Seattle, WA 98195-6460, USA. darcarr@u.washington.edu
Objective:
Determine whether preeclampsia is associated with developing diabetes.
Methods:
Subsequent diabetes was ascertained using ICD-9 codes, pharmacy and glucose data in a retrospective cohort study of 2,032 women with preeclampsia and 29,431 without preeclampsia.
Results:
During a median follow-up of 8.2 years, 342 women developed diabetes. Preeclampsia was associated with a higher risk of diabetes adjusting for age, primigravidity, and gestational diabetes (hazard ratio, HR 1.82, 95%CI 1.26, 2.62) and in women without gestational diabetes (n = 30,109; HR 1.86, 95%CI 1.22, 2.84).
Conclusion:
Women with preeclampsia have greater risk of developing diabetes, even in the absence of gestational diabetes.
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