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Isolation of Endothelial Progenitor Cells from Healthy Volunteers and Their Migratory Potential Influenced by Serum Samples After Cardiac Surgery
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Published on: February 14, 2017

Progenitors in motion: mechanisms of mobilization of endothelial progenitor cells

Lindsey Tilling1, Philip Chowienczyk, Brian Clapp

  • 1King's College London, London SE1 7EH, UK. lindsey.tilling@kcl.ac.uk

British Journal of Clinical Pharmacology
|October 22, 2009
PubMed

Endothelial progenitor cells are a population of bone marrow-derived mononuclear cells thought to engage in endothelial repair and hence are considered potential therapeutic agents in many pathological conditions. The mechanism of their exit from the bone marrow to the circulation and damaged tissues, termed mobilization, has not been fully elucidated. Despite this, several pharmacological interventions have been shown to influence mobilization of these specialized cells. Here we review the current understanding of their mobilization.

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