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Published on: May 19, 2020
Valve and great vessel stenosis: assessment with MR jet velocity mapping
P J Kilner1, D N Firmin, R S Rees
1Magnetic Resonance Unit, National Heart Hospital, London, England.
Abstract:
For measurement of poststenotic jet velocities with magnetic resonance (MR) imaging, the authors reduced the echo time (TE) of the field even-echo rephasing (FEER) velocity mapping sequence from 14.0 to 3.6 msec, so minimizing the problem of MR signal loss from turbulent fluid. In vitro use of rotating disk and stenotic flow phantoms confirmed that the 3.6-msec TE sequence enables accurate measurement of jet velocities of up to 6.0 m/sec (r = .996). Peak jet velocity measurements were made with MR imaging in 36 patients with stenosis of native heart valves (n = 9), conduits (n = 19), or Fontan connections (n = 2) or with aortic coarctation (n = 6). Peak velocity measurements made with MR imaging agreed well with measurements made with Doppler ultrasound (US), which were available in 18 cases (standard deviation = 0.2 m/sec). Velocity mapping with fast-echo MR imaging is likely to have considerable importance as a noninvasive means of locating and evaluating stenoses, particularly at sites inaccessible to US, but care must be taken to prevent errors caused by malalignment, signal loss, phase wrap, or partial-volume effects.
Insights
This study optimized magnetic resonance (MR) imaging for measuring poststenotic jet velocities by reducing echo time. The new method accurately quanties high velocities, offering a valuable noninvasive tool for evaluating stenoses.
Area of Science:
- Cardiovascular Imaging
- Medical Physics
- Fluid Dynamics
Background:
- Accurate measurement of poststenotic jet velocities is crucial for diagnosing and managing various cardiovascular conditions.
- Traditional magnetic resonance (MR) imaging techniques can suffer from signal loss in turbulent flow, limiting velocity quantification.
- Optimizing MR imaging parameters is essential for improving the diagnostic accuracy of flow assessment.
Purpose of the Study:
- To reduce echo time (TE) in the field even-echo rephasing (FEER) velocity mapping sequence for improved MR imaging of poststenotic jet velocities.
- To minimize MR signal loss caused by turbulent fluid flow.
- To validate the accuracy and clinical utility of the optimized MR imaging sequence.
Main Methods:
- Reduced the echo time (TE) of the FEER velocity mapping sequence from 14.0 to 3.6 msec.
- Utilized in vitro rotating disk and stenotic flow phantoms for validation.
- Performed peak jet velocity measurements in 36 patients with various stenotic conditions using MR imaging.
Main Results:
- The 3.6-msec TE sequence accurately measured jet velocities up to 6.0 m/sec in vitro (r = .996).
- MR imaging measurements showed good agreement with Doppler ultrasound (US) in 18 patients (standard deviation = 0.2 m/sec).
- The optimized MR sequence successfully quantified velocities in patients with native heart valve stenosis, conduits, Fontan connections, and aortic coarctation.
Conclusions:
- Fast-echo MR imaging velocity mapping is a significant advancement for noninvasively locating and evaluating stenoses.
- This technique is particularly valuable for assessing stenotic sites that are difficult to access with ultrasound.
- Careful attention to potential errors, including malalignment, signal loss, phase wrap, and partial-volume effects, is necessary for accurate interpretation.
Related Concept Videos
Mitral Regurgitation I: Introduction
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Stenosis I: Introduction
Mitral Stenosis II: Clinical features and Diagnostic Tests
Aortic Regurgitation I: Introduction
Aortic Regurgitation II: Clinical Features and Diagnostic Tests

