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Related Experiment Video

Updated: Jun 19, 2026

Minimally Invasive Surgical Decompression of Occipital Nerves
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Minimally Invasive Surgical Decompression of Occipital Nerves

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Craniotomy pain: trying to do better

Allan Gottschalk

    Anesthesia and Analgesia
    |October 22, 2009
    PubMed
    Summary

    No abstract available in PubMed .

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    Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...

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