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A case of infantile meningioangiomatosis with a separate cyst
Seong Ho Kim1, Soo Han Yoon, Jang Hee Kim
1Department of Neurosurgery, College of Medicine, Yeungnam University, Daegu, Korea.
Abstract:
Meningioangiomatosis (MA) is a rare congenital tumor that occurs mostly in 5-15 year old children. There have been only 5 cases previously reported that described the cystic nature within these tumors. We present a case of a MA accompanied by a separate macrocyst. A normally developed 2 year-old female patient presented with partial and generalized seizures. The brain computerized tomogram and magnetic resonance imaging revealed the presence of a calcified mass accompanied by a cyst in the right parietal area, surrounded by low density and high attenuation edema and hemorrhage. Upon right parietal craniotomy, a 1.6 cm x 1.2 cm x 0.5 cm sized plate-like, gray-white, slightly hard mass was seen and it was completely excised. Approximately 1 cm from the mass in the anterior lateral direction, a cyst was found and subsequent biopsy of the cyst wall revealed no tumor tissue, and therefore the cyst was not removed. Pathologic report demonstrated the meningioangiomatosis. Follow up examination 2 years later showed no recurrence of the tumor, and there was no evidence of neurological deficits. Authors suggest that cysts that arise in the surrounding tissues of tumors may not be tumor cysts, and do not require surgical removal.
Insights
Meningioangiomatosis (MA) is a rare pediatric tumor. This case highlights a MA with a separate cyst, suggesting non-tumor cysts may not need surgical removal.
Area of Science:
- Pediatric Neurosurgery
- Neuropathology
- Congenital Neoplasms
Background:
- Meningioangiomatosis (MA) is a rare congenital tumor typically affecting children aged 5-15.
- Previous reports on MA have infrequently described cystic components within the tumors.
Observation:
- A 2-year-old female presented with seizures, revealing a calcified mass with an associated cyst in the right parietal area.
- Imaging showed edema and hemorrhage surrounding the lesion.
- Surgical excision of the mass was performed, but the separate cyst was biopsied and left in situ due to absence of tumor tissue.
Findings:
- Pathological examination confirmed meningioangiomatosis.
- Two-year follow-up showed no tumor recurrence and no neurological deficits.
- The separate cyst did not exhibit tumor infiltration.
Implications:
- This case suggests that cysts adjacent to meningioangiomatosis may be distinct entities and not neoplastic.
- Non-neoplastic, separate cysts may not require surgical intervention, potentially reducing patient morbidity.
- Further investigation into the nature and management of cysts associated with MA is warranted.
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