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Related Concept Videos

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Mitochondria01:37

Mitochondria

Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
Connective Tissue Cell Types01:22

Connective Tissue Cell Types

Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...

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Related Experiment Video

Updated: Jun 19, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

Vitamin D and ageing.

Daniel P Hayes1

  • 1The Brooklyn Hospital Center, 121 Dekalb Avenue, Brooklyn, NY 11201, USA. dhayes@health.nyc.gov

Biogerontology
|October 22, 2009
PubMed
Summary
This summary is machine-generated.

Vitamin D plays a crucial role in healthy aging by mitigating age-related diseases. Research highlights its positive impact on biogerontology, suggesting its importance for the elderly.

Related Experiment Videos

Last Updated: Jun 19, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

Area of Science:

  • Gerontology and Nutritional Science
  • Biogerontology
  • Endocrinology

Background:

  • A significant revolution in understanding vitamin D's effects has occurred over the last 30-40 years.
  • Active vitamin D metabolites are known to control and ameliorate various pathologies.
  • Emerging evidence suggests a positive role for vitamin D in the aging process.

Purpose of the Study:

  • To present evidence for vitamin D's positive role in aging.
  • To explore biological mechanisms and specific examples of vitamin D's effects on age-related maladies.
  • To advocate for the consideration of vitamin D's role in biogerontology research.

Main Methods:

  • Review of laboratory and epidemiologic studies.
  • Detailed consideration of biological mechanisms of vitamin D action.
  • Analysis of specific human maladies influenced by vitamin D.

Main Results:

  • Substantive evidence indicates vitamin D positively influences the aging process.
  • Vitamin D appears to reduce susceptibility to chronic degenerative diseases in the elderly.
  • Biological mechanisms support vitamin D's role in mitigating age-related pathologies.

Conclusions:

  • Vitamin D plays a major positive role in biogerontology.
  • Gerontologists and biogerontology researchers should consider vitamin D's impact on aging.
  • Further research and consideration of vitamin D are recommended for healthy aging strategies.