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Published on: December 9, 2010
Biomarkers in Clinical Trials--SMi Conference. 23-24 September 2009, London, UK
1Thomson Reuters, Hatton Garden, London, EC1N 8JS, UK. glenda.walker@thomsonreuters.com
Summary
This conference report covers new developments in biomarkers for clinical trials. It highlights biomarker definitions, applications in drug development, and treatment outcomes, featuring selumetinib.
Area of Science:
- Biomarkers and Translational Science
- Clinical Trial Design and Drug Development
Background:
- The Biomarkers in Clinical Trials conference convened experts to discuss advancements in biomarker research.
- Key areas included the evolving definition and application of biomarkers.
Purpose of the Study:
- To summarize critical discussions from the conference on biomarker utility.
- To highlight the role of biomarkers in informing drug development decisions and enhancing patient treatment.
- To present a case study on the investigational drug selumetinib.
Main Methods:
- Review of selected presentations from the Biomarkers in Clinical Trials conference.
- Focus on discussions regarding biomarker definition, drug development support, and treatment outcome improvement.
- Inclusion of a case study involving selumetinib.
Main Results:
- The conference underscored the importance of clear biomarker definitions.
- Biomarkers were presented as crucial tools for supporting decision-making in drug development.
- Evidence suggests biomarkers can significantly improve patient treatment outcomes.
Conclusions:
- Biomarker development and application are rapidly advancing.
- Strategic use of biomarkers is essential for efficient drug development and personalized medicine.
- The Biomarkers Consortium aims to further standardize and promote biomarker utilization.

