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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

[Perioperative antiplatelet therapy of patients with coronary stents]

T Chatterjee1, I Akin, T C Rehders

  • 1HerzZentrum Hirslanden Zentralschweiz, Klinik St. Anna, Luzern. tushar.chatterjee@hirslanden.ch

Praxis
|October 22, 2009
PubMed

Insights

Stent thrombosis is a feared complication after coronary stent implantation. Discontinuing dual antiplatelet therapy before surgery increases risks of stent thrombosis, myocardial infarction, and death.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiovascular Surgery

Background:

  • Stent thrombosis is a critical complication following coronary stent implantation, often leading to myocardial infarction and high mortality.
  • Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is the standard to prevent stent thrombosis post-procedure.

Purpose of the Study:

  • To review current data on perioperative complications in patients who have undergone percutaneous coronary intervention (PCI).
  • To highlight the increased risks associated with surgery soon after PCI and DAPT discontinuation.

Main Methods:

  • Review of current literature and clinical data.
  • Analysis of complication rates related to surgical timing and DAPT status post-PCI.

Main Results:

  • Surgery increases the risk of stent thrombosis, myocardial infarction, and death, especially when performed early after PCI.
  • Preoperative discontinuation of DAPT further elevates the incidence of these perioperative complications.

Conclusions:

  • Patients require careful management regarding the timing of surgery after PCI.
  • Maintaining DAPT perioperatively is crucial to mitigate risks of adverse cardiovascular events.

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