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Operation of a Benchtop Bioreactor

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Published on: September 12, 2013

Industrial biotechnology: tools and applications.

Weng Lin Tang¹, Huimin Zhao

¹Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

Biotechnology Journal

|October 22, 2009

Summary

Industrial biotechnology uses enzymes and microbes to create chemicals from renewable resources, reducing waste and energy use. Key tools like protein engineering and synthetic biology are driving its growth in various industries.

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Area of Science:

Industrial biotechnology
Biochemical engineering
Sustainable chemistry

Background:

Industrial biotechnology offers sustainable alternatives to traditional chemical manufacturing.
It utilizes enzymes and microorganisms for producing valuable compounds from renewable feedstocks.
The field is expanding due to its environmental benefits, including reduced energy consumption and waste.

Purpose of the Study:

To review essential tools in industrial biotechnology.
To showcase successful applications of these tools in producing key chemicals.
To project the future adoption of industrial biotechnology across sectors.

Main Methods:

Protein engineering for enzyme optimization.
Metabolic engineering for microbial strain improvement.
Synthetic biology for designing novel biological pathways.
Systems biology for understanding cellular networks.
Downstream processing for product purification.

Main Results:

Successful production of 1,3-propanediol using engineered microorganisms.
Efficient synthesis of lactic acid for bioplastics.
Development of advanced biofuel production methods.
Demonstration of integrated approaches combining multiple biotechnological tools.

Conclusions:

Industrial biotechnology provides sustainable and efficient routes for chemical production.
The integration of advanced tools like synthetic biology is crucial for innovation.
Widespread adoption by chemical, pharmaceutical, food, and agricultural industries is anticipated.