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Updated: Jun 19, 2026

Isolation, Culture, and Imaging of Human Fetal Pancreatic Cell Clusters
Published on: May 18, 2014
ANP and insulin presence in human foetal pancreas
Biagio Valentino1, Diego Lipari, Giovanni Peri
1Dipartimento di Medicina sperimentale, Sezione Anatomia umana, Università di Palermo. bigvalentino@libero.it
Abstract:
Aim of this work is to investigate the presence of Atrial natriuretic peptide (ANP) and insulin in human foetal pancreas from not diabetic and diabetic mothers. The data literature evidenced relationship between serum ANP and insulin. The our work carried out on sections immunostained for ANP and insulin showed positivity for ANP and insulin in beta-cells of pancreas from diabetic mothers, while positivity for insulin in beta-cells of foetuses from not diabetic mothers. Results indicate that the insulin presence stimulates the ANP synthesis in pancreas of human foetuses from diabetic mothers.
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