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Updated: Jun 19, 2026

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Published on: September 20, 2024
Focal clinical and electroencephalographic features in patients with juvenile myoclonic epilepsy
S S Jayalakshmi1, B Srinivasa Rao, S Sailaja
1Department of Neurology, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad, Andhra Pradesh, India. sita_js@hotmail.com
Objective:
To identify prevalence and factors associated with occurrence of focal clinical and electroencephalogram (EEG) abnormalities in patients with juvenile myoclonic epilepsy (JME).
Materials And Methods:
Clinical asymmetries in the seizures and focal EEG abnormalities were analyzed in 266 patients with JME.
Results:
All the patients had myoclonic jerks (MJ) and generalized tonic-clonic seizures (GTCS); 56 (21%) had absence seizures. Asymmetry in clinical seizures was reported in 45 (16.9%) and focal EEG abnormalities were noted in 92 (45.5%) patients. Amplitude asymmetry or focal onset of generalized discharges was noted in 41 (44.6%) and independent focal EEG abnormalities in 30 (32.6%) patients. A statistically significant association was seen with the presence of GTCS and MJ (P = 0.007), a family history of epilepsy (P = 0.001) and drug resistance (P = 0.04) and the occurrence of focal EEG abnormalities.
Conclusion:
Patients with JME showed focal clinical and EEG features. These features should not be misinterpreted as indicative of partial epilepsy.
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