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Updated: Jun 19, 2026

Collection and Extraction of Occupational Air Samples for Analysis of Fungal DNA
Published on: May 2, 2018
Point-source outbreak of coccidioidomycosis in construction workers
K C Cummings1, A McDowell, C Wheeler
1Infectious Diseases Branch, Division of Communicable Disease Control, Center for Infectious Diseases, California Department of Public Health, Richmond, CA, USA. kate.cummings@cdph.ca.gov
Construction workers excavating soil in endemic areas are at high risk for coccidioidomycosis. Implementing protective measures is crucial to prevent inhalation of Coccidioides spp. spores.
Area of Science:
- Mycology
- Infectious Diseases
- Occupational Health
Background:
- Coccidioidomycosis is caused by inhaling Coccidioides spp. spores.
- Endemic areas include specific soil and dust environments.
Purpose of the Study:
- Investigate a coccidioidomycosis outbreak in construction workers.
- Assess disease incidence and risk factors.
Main Methods:
- Case investigation of a 12-person construction crew.
- Serological testing and chest radiography.
- Review of exposure history and environmental factors.
Main Results:
- Ten of 12 workers developed coccidioidomycosis symptoms.
- Eight workers had confirmed disease; one had disseminated infection.
- No workers used respiratory protection during excavation.
Conclusions:
- Soil excavation in endemic areas poses a significant risk for coccidioidomycosis.
- Respiratory protection is essential during soil-disrupting activities.
- Preventive measures should be implemented even in areas with historic disease evidence.
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