Related Experiment Video
Updated: Jun 19, 2026
A High-throughput Compatible Assay to Evaluate Drug Efficacy against Macrophage Passaged Mycobacterium tuberculosis
Published on: March 24, 2017
Comparison of the performance of two mycobacteriophage D29-based protocols for fluoroquinolone susceptibility testing
Emma J Stella1, Agustina I de la Iglesia, Héctor R Morbidoni
1Cátedra de Microbiología, Facultad de Ciencias Médicas, Universidad Nacional de Rosario, 2000 Rosario, Argentina.
Abstract:
We tested a mycobacteriophage D29-based method for fluoroquinolone susceptibility assessment in clinical isolates of Mycobacteriumtuberculosis. The method was incapable of identifying susceptible strains as such, although a slightly different published protocol successfully identified resistant and susceptible strains. Thus, caution is necessary when choosing an "in-house" D29-based protocol for testing of drug resistance.
