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Appendicitis

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

Appendicitis-I: Introduction

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...

Appendicitis-II: Diagnostic Studies and Management

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...

Assessment of the Rectum and Anus

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...

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Updated: Jun 19, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

[Appendiceal tumors found at appendectomy].

D Goere¹, D Elias

¹Département de chirurgie oncologique, institut Gustave-Roussy, 39, rue Camille-Desmoulins, 94805 Villejuif cedex, France. diane.goere@igr.fr

Journal De Chirurgie

|October 23, 2009

Summary

This summary is machine-generated.

Appendiceal tumors include neuroendocrine tumors (most common), adenomas, and adenocarcinomas. Mucinous types can spread, potentially causing pseudomyxoma peritonei, requiring surgery and chemotherapy.

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Area of Science:

Gastroenterology and Surgical Oncology

Context:

Appendiceal tumors encompass adenomas, adenocarcinomas, and neuroendocrine tumors.
Neuroendocrine tumors (carcinoids) represent the most prevalent type, accounting for two-thirds of all appendiceal neoplasms.

Purpose:

To delineate the characteristics and management of appendiceal tumors, focusing on their histologic subtypes and potential complications.

Summary:

Appendiceal tumors present in three main histologic forms: adenoma, adenocarcinoma, and neuroendocrine tumor. Neuroendocrine tumors are the most common. Adenomas and adenocarcinomas are rare and often feature a predominant mucinous component, with a propensity for intraperitoneal dissemination.
Rupture of mucinous appendiceal tumors can lead to pseudomyxoma peritonei, a condition necessitating complete surgical resection and hyperthermic intraperitoneal chemotherapy.
Unruptured, aggressive appendiceal tumors warrant a carcinologic right hemicolectomy for the appendix.

Impact:

This information aids in understanding the diverse nature of appendiceal tumors and guides appropriate surgical and oncologic treatment strategies.
Highlights the critical distinction between tumor types for effective management and prevention of complications like pseudomyxoma peritonei.