Related Experiment Video
Updated: Jun 19, 2026

Modeling Posthemorrhagic Hydrocephalus of Prematurity in Rats
Published on: March 28, 2025
Recurrent obstructive hydrocephalus in a 4-month-old infant
Danilo Castellano-Chiodo1, Piero Pavone, Andrea Domenico Praticò
1Unit of Clinical Paediatrics, Department of Paediatrics, University of Catania, Catania, Italy.
Insights
Recurrent obstructive hydrocephalus in infants, a rare condition, was successfully treated with endoscopic third ventriculostomy. This minimally invasive surgery resolved the blockage, leading to rapid neurological improvement and normal development.
Area of Science:
- Pediatric Neurosurgery
- Pediatric Urology
Background:
- Obstructive hydrocephalus in children typically results from tumors, bleeding, cysts, meningitis, or poisoning.
- Recurrent obstructive hydrocephalus is exceptionally rare.
Observation:
- A 4-month-old boy experienced multiple episodes of obstructive hydrocephalus due to intermittent blockage of cerebrospinal fluid flow.
- The child also had congenital left hydronephrosis secondary to ureteropelvic junction stenosis.
Findings:
- Endoscopic third ventriculostomy was performed, resulting in transient central diabetes insipidus.
- Post-surgical neurological symptoms rapidly improved.
Implications:
- Endoscopic third ventriculostomy offers a viable treatment for rare cases of recurrent obstructive hydrocephalus in infants.
- Successful management of hydrocephalus can lead to normal psychomotor development in affected children.
Introduction:
Transient, recurrent or permanent causes of hydrocephalus in children are usually due to tumours, cerebral bleeding or colloid cysts and complications of infectious meningitis or secondary to poisoning. Recurrent, obstructive hydrocephalus is very rare.
Case Report:
We report a 4-month-old boy who suffered at least three different episodes of obstructive hydrocephalus presumably caused by intermittent valvular blockage of the normal aqueduct cerebrospinal flow as indirectly demonstrated by serial standard and dynamic brain imaging studies. In addition, he had congenital left hydronephrosis secondary to congenital ureteropelvic junction stenosis. The child underwent an endoscopic third ventriculostomy with only transient post-surgical complications (i.e. central diabetes insipidus).
Discussion:
The neurological symptoms rapidly improved after surgery, and the child is currently doing well with normal psychomotor development.
Related Concept Videos
Increased Intracranial Pressure l: Introduction
Increased Intracranial Pressure ll: Pathophysiology
Pyloric Obstruction
