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Related Concept Videos

Cystic Fibrosis: Pathogenesis01:23

Cystic Fibrosis: Pathogenesis

Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation, but...
Fetal Circulation01:14

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
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Embryonic Connective Tissues

During early development, the embryo forms two types of connective tissues— the mesenchyme and mucoid connective tissue.
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Gallbladder01:17

Gallbladder

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Urinary Tract Calculi I: Introduction

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Cystic Fibrosis: Management

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Related Experiment Video

Updated: Jun 19, 2026

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst
03:10

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst

Published on: March 31, 2023

[Umbilical cord cyst--should it concern us?].

Rachel Zangen1, Haim Yaffe

  • 1Department of Obstetrics and Gynecology, Bikur Holim Medical Center, Jerusalem, Israel. rachelzangen@yahoo.com

Harefuah
|October 24, 2009
PubMed
Summary

Prenatal diagnosis of umbilical cord cysts requires careful evaluation. First-trimester cysts may indicate congenital malformations, while later-trimester cysts, especially with other anomalies, suggest chromosomal issues, necessitating fetal karyotyping.

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Generation and Quantitative Characterization of Functional and Polarized Biliary Epithelial Cysts
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Generation and Quantitative Characterization of Functional and Polarized Biliary Epithelial Cysts

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Last Updated: Jun 19, 2026

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst
03:10

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst

Published on: March 31, 2023

Generation and Quantitative Characterization of Functional and Polarized Biliary Epithelial Cysts
09:55

Generation and Quantitative Characterization of Functional and Polarized Biliary Epithelial Cysts

Published on: May 16, 2020

Area of Science:

  • Perinatology
  • Fetal Medicine
  • Medical Imaging

Background:

  • Sonographic technology advances improve prenatal detection of fetal anomalies.
  • First-trimester umbilical cord cystic masses occur in 0.4%-3.4% of pregnancies.
  • Second- and third-trimester umbilical cord cysts are rare, with unknown prevalence.

Purpose of the Study:

  • To investigate the implications of prenatal umbilical cord cysts.
  • To define appropriate prenatal follow-up strategies for these findings.

Main Methods:

  • Case report of a second-trimester umbilical cord cyst diagnosis.
  • Literature review on umbilical cord cysts and associated anomalies.
  • Analysis of follow-up protocols based on gestational age and associated findings.

Main Results:

  • First-trimester cysts are linked to congenital malformations, not typically chromosomal anomalies.
  • Second- and third-trimester cysts with additional malformations strongly correlate with chromosomal anomalies (e.g., trisomy 18).
  • Isolated second- or third-trimester cysts also show association with chromosomal anomalies, warranting karyotyping.

Conclusions:

  • Transient first-trimester cysts require detailed sonographic evaluation for malformations.
  • Routine karyotyping may not be necessary for isolated first-trimester cysts.
  • Second- and third-trimester umbilical cord cysts, especially with other anomalies, necessitate fetal karyotyping; isolated cysts require serial sonographic monitoring for good prognosis.