Comparison of postoperative wavefront aberrations after NIDEK CXIII optimized aspheric transition zone treatment and...

To compare higher order aberrations of aspheric or wavefront-guided myopic LASIK.

This was a prospective, randomized study of a myopic LASIK cohort that was subdivided into two groups; 12 eyes were treated with the optimized aspheric transition zone algorithm (OATz group) and 11 eyes were treated with wavefront-guided optimized path difference custom aspheric treatment (OPDCAT group). Corneal asphericity and higher order aberrations root-mean-square were compared between groups before, 1 month, and 3 months after LASIK. Student t test was used to assess differences between groups. P<.05 was considered statistically significant.

At 3 months postoperatively, all eyes in both groups had spherical equivalent refraction of +/-0.50 diopters (D). Mean higher order aberration increased by 0.18 microm postoperatively in the OATz group (P<.05) and decreased by 0.04 microm in the OPDCAT group (P=.819). A statistically significant increase in spherical aberration was noted in the OATz group only (P<.05). Asphericity showed a statistically significant difference between the two groups postoperatively (P<.05). There was a greated tendency for increased higher order aberrations in eyes with <0.30 microm of higher order aberrations preoperatively in the OPDCAT group. The reverse tendency was observed in the OATz group.

OPDCAT induced minimal changes in spherical aberration due to lower changes in corneal asphericity compared to the OATz group. Eyes with <0.30 microm of higher order aberrations preoperatively are likely better candidates for the OATz algorithm than OPDCAT.