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8;21 translocation with duplication of the der(21) in a patient with myelomonocytic leukemia
M J Auger1, F M Ross, M J Mackie
1Department of Haematology, Western General Hospital, Edinburgh.
Cancer Genetics and Cytogenetics
|January 1, 1991
Abstract:
An 8;21 translocation with duplication of the der(21) is described in a 72-year-old man who presented with features of chronic myelomonocytic leukemia. Progression to acute myelomonocytic leukemia occurred within one month of diagnosis. The possible prognostic significance of the t(8;21) with duplicated der(21) in myelodysplasia is discussed.