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Related Experiment Videos

Gastric volume and acidity at caesarean section.

J G Brock-utne, A J Barclay, P J Houlton

    South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
    |July 23, 1977
    PubMed
    Summary

    Pulmonary acid aspiration, or Mendelson's syndrome, can occur during obstetric anesthesia. To prevent this, antacid therapy should be repeated if general anesthesia is delayed more than 2 hours after initial administration.

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    Area of Science:

    • Anesthesiology
    • Obstetrics
    • Gastroenterology

    Background:

    • Pulmonary acid aspiration (Mendelson's syndrome) is a risk during obstetric anesthesia.
    • Gastric acid aspiration can lead to severe pulmonary complications.

    Purpose of the Study:

    • To evaluate the duration of gastric pH elevation after alkaline ingestion in obstetric patients.
    • To determine optimal timing for antacid therapy to prevent Mendelson's syndrome.

    Main Methods:

    • Gastric aspirates from 70 mothers undergoing cesarean section were analyzed for pH and volume.
    • Patients were grouped based on the time of gastric aspiration post-antacid ingestion.
    • Gastric pH and volume were measured to assess 'safe' conditions (pH > 3.5, volume < 25 ml).

    Main Results:

    • A safe gastric pH (> 3.5) was maintained in all patients up to 2 hours after antacid ingestion.
    • At 2.5 hours post-antacid ingestion, 50% of patients had gastric volumes exceeding 25 ml with a pH < 3.5.

    Conclusions:

    • Antacid therapy provides a safe gastric environment for up to 2 hours in obstetric patients.
    • Repeated gastric aspiration and alkaline regimen are recommended if general anesthesia induction is delayed beyond 2 hours post-antacid therapy.

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