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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...

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Related Experiment Videos

[Cutaneous botryomycosis: case report].

Weber Soares Coelho1, Lucia Martins Diniz, João Basílio de Souza Filho

  • 1Sociedade Brasileira de Dermatologia. dr.webersoares@yahoo.com.br

Anais Brasileiros De Dermatologia
|October 24, 2009
PubMed
Summary

Botryomycosis, a chronic bacterial skin infection, typically involves Staphylococcus aureus. This case highlights exuberant lesions successfully treated with sulphamethoxazole-trimethoprim.

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Microbiology

Background:

  • Botryomycosis is a rare, chronic bacterial infection affecting skin and subcutaneous tissues.
  • Characterized by granulomatous inflammation and suppurative lesions with characteristic grains.

Observation:

  • A case of botryomycosis presented with extensive lesions on the right leg.
  • The affected limb showed increased volume, fibrous consistency, and multiple fistulae draining characteristic white-yellowish grains.

Findings:

  • The primary pathogen identified was Staphylococcus aureus.
  • Other potential pathogens like Pseudomonas aeruginosa and Escherichia coli were considered.

Implications:

  • This case demonstrates a severe presentation of botryomycosis.

Related Experiment Videos

  • Successful treatment was achieved using the antibiotic combination sulphamethoxazole-trimethoprim, highlighting its therapeutic potential.