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Published on: April 21, 2019
High sensitization rate to food allergens in breastfed infants with atopic dermatitis
Youngshin Han1, Sang-Jin Chung, Jihyun Kim
1Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Background:
The differences in the characteristics of breastfed and formula fed individuals with allergy have been addressed in few studies and remain controversial.
Objective:
To evaluate the effect of breastfed on the development of food allergy and sensitization against food allergens in infants with atopic dermatitis (AD).
Methods:
We reviewed 143 infants (77 boys and 66 girls) with AD who were younger than 6 months and were classified into the following 3 groups based on the type of feeding they received: breastfed, mixed feeding, and formula fed. All infants had never been fed egg or soy. The total and specific IgE levels were then assessed using a commercially available assay.
Results:
The total IgE level (P = .004) and egg specific IgE level (P = .002) were significantly higher in the BF group than in the FF group. The rate of sensitization to egg (P = .001) was also significantly higher in the BF group when compared with the FF group, as was the egg allergy rate (P = .004).
Conclusion:
Our results suggest that breastfeeding might not always be beneficial in allergy prevention in some high-risk infants.
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