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Related Concept Videos

Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document any history...
Autoimmune Disorders01:29

Autoimmune Disorders

Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune system...
Myocarditis IV: Nursing Management01:22

Myocarditis IV: Nursing Management

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Related Experiment Video

Updated: Jun 19, 2026

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
09:43

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Published on: June 8, 2022

Updates on lupus and pregnancy.

Jill P Buyon1

  • 1Division of Rheumatology, Department of Medicine, NYU Hospital for Joint Diseases, New York University Langone Medical Center, New York, New York 10019, USA. jill.buyon@nyumc.org

Bulletin of the NYU Hospital for Joint Diseases
|October 27, 2009
PubMed
Summary
This summary is machine-generated.

Women with systemic lupus erythematosus (SLE) planning pregnancy should monitor maternal, placental, and fetal health. Stable patients have low flare rates, but renal disease and specific antibodies require careful management for successful pregnancy outcomes.

Related Experiment Videos

Last Updated: Jun 19, 2026

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
09:43

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Published on: June 8, 2022

Area of Science:

  • Reproductive Medicine
  • Rheumatology
  • Maternal-Fetal Medicine

Background:

  • Systemic lupus erythematosus (SLE) presents unique challenges during pregnancy.
  • Management requires careful consideration of maternal, placental, and fetal well-being.

Purpose of the Study:

  • To review pregnancy management for women with SLE.
  • To identify risks and protective factors for maternal and fetal outcomes.

Main Methods:

  • Literature review focusing on pregnancy in women with SLE.
  • Analysis of maternal, placental, and fetal complications.
  • Evaluation of risk factors and management strategies.

Main Results:

  • Clinically stable SLE patients have low pregnancy flare rates.
  • Pre-existing renal disease (creatinine > 2 mg/dl) increases risks of hypertension, preeclampsia, and fetal loss.
  • Discontinuation of ACE inhibitors, ARBs, and mycophenolate is crucial.
  • Elevated sVEGF-1 may predict preeclampsia.
  • Lupus anticoagulant is a strong predictor of pregnancy complications.
  • Anti-SSA/Ro antibodies carry a 2% risk of congenital heart block, with an 18% recurrence rate.

Conclusions:

  • Pregnancy in SLE requires individualized management based on disease stability and specific risk factors.
  • Close monitoring for renal function, preeclampsia, and fetal complications is essential.
  • Specific antibody profiles necessitate targeted surveillance and intervention strategies, particularly for neonatal lupus complications.