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Updated: Jun 19, 2026
08:40
Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
[Extraintestinal manifestations in inflammatory bowel disease]
Signe Larsen1, Klaus Bendtzen, Ole Haagen Nielsen
1c/o Ole Haagen Nielsen, Gastroenheden, Medicinsk Sektion, Herlev Hospital, Herlev Ringvej 75, DK-2730 Herlev, Denmark. signelarsen@stud.ku.dk
Ugeskrift for Laeger
|October 27, 2009
Summary
Chronic inflammatory bowel disease (IBD) frequently causes joint, skin, and eye issues. Effective treatments exist for common IBD-related conditions like arthritis and skin lesions.
Area of Science:
- Gastroenterology
- Rheumatology
- Dermatology
- Ophthalmology
Context:
- Chronic inflammatory bowel disease (IBD) encompasses a range of conditions, including Crohn's disease and ulcerative colitis.
- Extraintestinal manifestations (EIMs) are common in IBD patients, impacting various organ systems beyond the gastrointestinal tract.
- Understanding EIMs is crucial for comprehensive IBD management.
Purpose:
- To review the common extraintestinal manifestations associated with chronic inflammatory bowel disease.
- To highlight the key rheumatologic, dermatologic, and ophthalmologic complications of IBD.
- To discuss current therapeutic strategies for managing IBD-related EIMs.
Summary:
- Extraintestinal manifestations frequently occur in chronic inflammatory bowel disease, affecting joints, skin, and eyes.
- Peripheral arthritis and axial arthropathies are the most common rheumatologic issues.
- Dermatologic manifestations include erythema nodosum and pyoderma gangraenosum; ophthalmologic complications involve episcleritis, iridocyclitis, and uveitis.
- Conventional medications and biological therapies demonstrate efficacy in treating conditions such as peripheral arthritis, pyoderma gangraenosum, and episcleritis.
Impact:
- Provides a concise overview of IBD-associated extraintestinal manifestations.
- Informs clinicians about the spectrum of non-gastrointestinal complications in IBD.
- Supports evidence-based treatment decisions for managing IBD comorbidities.
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