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Developing outcome measures for paediatric rheumatic diseases

Hermine I Brunner1, Angelo Ravelli

  • 1Cincinnati Children's Hospital Medical Center, University of Cincinnati, William Rowe Division of Rheumatology, Cincinnati, OH 45229-3039, USA. hermine.brunner@cchmc.org

Best Practice & Research. Clinical Rheumatology
|October 27, 2009
PubMed

Insights

This review outlines developing and validating outcome measures for pediatric rheumatic diseases. It details methods for creating reliable and valid assessment tools for conditions like juvenile idiopathic arthritis.

Area of Science:

  • Rheumatology
  • Pediatrics
  • Health Outcomes Research

Background:

  • Assessing pediatric rheumatic diseases requires robust outcome measures.
  • Existing measures may not fully capture disease state and progression.
  • Standardized tools are crucial for clinical trials and patient management.

Purpose of the Study:

  • To provide a theoretical framework for developing outcome measures in pediatric rheumatic diseases.
  • To review newly developed and validated outcome measures for these conditions.
  • To guide researchers and clinicians in selecting and utilizing appropriate assessment tools.

Main Methods:

  • Literature review of scale development methodologies.
  • Description of item generation, reduction, reliability, and validation processes.
  • Synthesis of newly developed outcome measures and their validation status.

Main Results:

  • Detailed theoretical approach to outcome measure development.
  • Overview of various outcome measures including disease activity scores, functional assessments, and quality of life tools.
  • Discussion on the validation status of different measures for specific pediatric rheumatic diseases.

Conclusions:

  • Standardized and validated outcome measures are essential for pediatric rheumatic diseases research and care.
  • The review provides a comprehensive guide to developing and applying these measures.
  • Further development and validation are ongoing for various disease-specific tools.

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