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11,12-secoprostaglandins. 4. 7-(N-alkylmethanesulfonamido) heptanoic acids
Journal of Medicinal Chemistry
|October 1, 1977
Abstract:
A series of 7-(N-alkylmethanesulfonamido) heptanoic acids has been prepared which represents an extension of our 8-aza-11,12-secoprostaglandin studies. The studies. The compounds mimic the natural prostaglandins in that they markedly stimulate cAMP formation in the mouse ovary assay.