Familial Takayasu's arteritis in female siblings

Takayasu's arteritis (TA) is a rare chronic vasculitis of the aorta and its main branches. Infectious agents or autoimmunity are thought to influence the pathophysiology. Ethnic preponderance in East Asia and usually affects young Asian women suggesting a possible role of genetic factor in the etiology. We present a rare case of familial TA in female siblings with the involvement of the main branches of aortic arch and renal arteries described by three-dimensional computed tomography (3D-CT). This case is rare familial TA in female siblings with CT angiography, which is feasible in diagnosis and informative for the stage of TA.