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Expression of Exogenous Cytokine in Patient-derived Xenografts via Injection with a Cytokine-transduced Stromal Cell Line
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Published on: May 10, 2017

Adipocytokines in relation to Hodgkin lymphoma in children

Eleni Th Petridou1, Nick Dessypris, Paraskevi Panagopoulou

  • 1Department of Hygiene, Epidemiology and Medical Statistics, Athens University Medical School, Athens, Greece. epetrid@med.uoa.gr

Pediatric Blood & Cancer
|October 27, 2009
PubMed

This case-control study aims to explore the association of serum adiponectin/leptin with childhood Hodgkin lymphoma (HL). Study participants were 75 children with histologically confirmed HL, registered in the Nationwide Registry for Childhood Haematological Malignancies and 75 age- and gender-matched controls. Multiple conditional logistic regression analyses were performed, adjusting for sociodemographic and lifestyle parameters. Adiponectin levels were consistently higher among cases in all models with ORs >1.25; 95% CIs ranging from 0.9 to 1.8 and P-values from 0.09 to 0.20. By contrast, there was no association of serum leptin with HL. In conclusion, elevated serum adiponectin might be a risk factor for childhood HL.

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