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Published on: August 22, 2012
[Hydatidosis relapse in children--clinical and epidemiological study]
Corina Constantin1, Simona Rădulescu, Carmen-Michaela Creţu
1Spitalul Clinic Colentina, Secţia de Boli Parazitare.
Insights
Children with hydatidosis require extended 2-year post-operative monitoring for relapses, primarily affecting the liver and lungs. Early detection via imaging and serology, alongside antiparasitic treatment, is crucial for recovery.
Area of Science:
- Pediatric Surgery
- Infectious Diseases
- Parasitology
Context:
- Hydatidosis, a parasitic disease caused by Echinococcus granulosus, poses significant challenges in pediatric populations.
- Recurrence of hydatidosis after surgical intervention necessitates careful long-term management strategies.
Purpose:
- To analyze relapse patterns in pediatric patients operated for hydatid cyst.
- To determine optimal post-operative monitoring duration and diagnostic methods for hydatidosis recurrence.
Summary:
- This retrospective study involved 160 children with hydatid cyst, 110 of whom underwent surgery, with 35 experiencing relapses.
- Relapses predominantly occurred within a 2-year post-operative period, with the liver and lungs being the most frequently affected organs.
- Secondary hydatidosis was more common at a distance from the primary site.
- Diagnostic approaches include imaging (ultrasound, radiography) and serological surveillance for IgG antibodies.
- Pre- and post-operative antiparasitic treatment can complement surgical management.
Impact:
- Highlights the importance of extended post-operative surveillance for pediatric hydatidosis.
- Informs clinical practice regarding optimal monitoring timelines and diagnostic modalities.
- Emphasizes the role of multimodal treatment including antiparasitic therapy for improved patient outcomes.
Abstract:
This study is a retrospective inquiry among children operated for hydatid cyst which were diagnosed with at least one relapse episode. The study-group consisted of 160 children out of which 110 were submitted to at least one surgical procedure and 35 out of 110O presented hydatidosis relapses. The post-operative monitorization of children with hydatidosis must be extended over a 2-year-period (69.29%) time during which most of the relapses occur. The organs being most frequently affected are primary the liver and secondary the lung. The secondary hydatidosis is more frequent "at distance" from the residual cavity than "in situ". The parasitic control is centered on the imagistic test: abdominal ultrasound, lungradiography and the serological surveillance of specific antibodies of IgG class which can remain positive during the whole life with decreasing titers in time. The antiparasitic treatment pre- and post- operative can complete the therapeutic schedule in the case of hydatidosis in order to assure the recovery.
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