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Updated: Jun 19, 2026

Modeling Cataract Surgery in Mice
Published on: December 1, 2023
Cataract surgery under infliximab therapy in a patient with Behçet's disease
Eriko Noda1, Shigeki Yamanishi, Atsushi Shiraishi
1Department of Ophthalmology, Ehime University School of Medicine, Shitsukawa, Toon, Ehime, Japan. erikon@matsuyama.jrc.or.jp
Purpose:
To report a case of a successful cataract surgery outcome in a patient with Behçet's disease (BD) without postoperative inflammation under infliximab therapy.
Case:
A 40-year-old man who had frequent episodes of hypopyon uveitis despite immunosuppressive therapy underwent cataract surgery. Infliximab (5 mg/kg) was given intravenously to prevent inflammation during the perioperative period. After the initial administration, infliximab was given at 2 and 6 weeks, and then it was given at 8 weeks intervals thereafter. The patient underwent cataract surgery in both eyes at the midpoint of the 8 weeks duration schedule with an uneventful postoperative clinical course for up to 12 months except for the contraction of the anterior capsule in both eyes and posterior capsule opacification in 1 eye.
Conclusions:
Infliximab therapy may be effective when performing cataract surgery on BD patients who have uncontrollable uveitis.
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