Related Experiment Video
Updated: Jun 19, 2026

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction
Published on: April 1, 2019
Bilateral deepening of upper lid sulcus from topical bimatoprost therapy
Jason C S Yam1, Nancy S Y Yuen, Clement W N Chan
1Department of Ophthalmology, Tung Wah Eastern Hospital, Prince of Wales Hospital, Hong Kong, People's Republic of China. jasonyam418@yahoo.com.hk
Purpose:
To report a new adverse effect related to treatment with bimatoprost.
Method:
Case report. A 43-year-old Asian female with bilateral glaucoma was noticed to have bilateral deepening of upper lid sulcus 3 months after beginning treatment with bimatoprost 0.03%.
Results:
Bimatoprost was discontinued due to cosmetic reasons, and there was improvement of the lid sulcus deepening bilaterally 4 weeks after stopping the drug.
Conclusions:
Deepening of upper lid sulcus is one of the adverse effects related to treatment with bimatoprost. This effect may be more prominent in Asians who have relatively full upper lid sulcus.
Related Concept Videos
Angle Closure Glaucoma: Treatment
Glaucoma: Overview
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
