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Related Experiment Video

Updated: Jun 19, 2026

Methods for Detecting Cough and Airway Inflammation in Mice

Methods for Detecting Cough and Airway Inflammation in Mice

Published on: August 2, 2024

[Headache after coughing: consider cough headache].

L G Bert Nap¹, J S P Peter van den Berg, Gosse de Jong

¹Isala klinieken, afd. Neurologie, Zwolle, The Netherlands.

Nederlands Tijdschrift Voor Geneeskunde

|October 28, 2009

Summary

This summary is machine-generated.

Primary cough headache, triggered by activities like coughing, can be effectively treated with indomethacin and a proton pump inhibitor. Differentiating it from secondary causes is crucial for proper management.

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Area of Science:

Neurology
Clinical Medicine

Background:

Headaches triggered by activities increasing intracranial pressure, such as coughing, warrant investigation.
Primary cough headache is a diagnosis of exclusion, requiring differentiation from secondary causes.

Observation:

Two patients presented with headaches linked to intracranial pressure-increasing activities.
One patient received prompt diagnosis and treatment for primary cough headache.
The second patient's symptoms persisted despite treatment for rhinosinusitis before a primary cough headache diagnosis.

Findings:

Both patients achieved pain relief with indomethacin and a proton pump inhibitor, confirming primary cough headache.
Indomethacin serves as a diagnostic and therapeutic trial for suspected primary cough headache.

Implications:

Early diagnosis and appropriate treatment, including indomethacin, can resolve primary cough headache.
Distinguishing primary cough headache from secondary causes necessitates careful evaluation and potentially further investigation.