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Updated: Jun 19, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
[Babies with cranial deformity]
Michelle M W Feijen1, Edith A W M Habets Claessens, Anke J Leenders Dovens
1Maastricht Universitair Medisch Centrum, Afd. Plastische Chirurgie, Maastricht, The Netherlands. michellefeijen@gmail.com
Insights
Positional plagiocephaly and brachycephaly are cranial vault shape changes in infants. Early physiotherapy or helmet therapy can effectively treat these conditions, addressing the increased incidence linked to safe infant sleep practices.
Area of Science:
- Pediatrics
- Developmental Biology
- Orthopedics
Background:
- Positional plagiocephaly and brachycephaly involve cranial vault asymmetry.
- Incidence has risen due to back-sleeping recommendations for SIDS prevention.
Observation:
- Deformational plagiocephaly diagnosed in a 4-month-old.
- Deformational brachycephaly diagnosed in a 5-month-old.
Findings:
- Conservative treatments include physiotherapy and helmet therapy.
- Physiotherapy is recommended for positional preferences.
- Moulding helmet therapy is an option for significant cranial deformities by 5 months.
Implications:
- Early intervention is crucial for managing positional cranial deformities.
- Increased awareness and timely treatment can mitigate long-term effects.
- This highlights the importance of monitoring infant head shape development.
Abstract:
Plagiocephaly was diagnosed in a baby aged 4 months and brachycephaly in a baby aged 5 months. Positional or deformational plagio- or brachycephaly is characterized by changes in shape and symmetry of the cranial vault. Treatment options are conservative and may include physiotherapy and helmet therapy. During the last two decades the incidence of positional plagiocephaly has increased in the Netherlands. This increase is due to the recommendation that babies be laid on their backs in order to reduce the risk of sudden infant death syndrome. We suggest the following: in cases of positional preference of the infant, referral to a physiotherapist is indicated. In cases of unacceptable deformity of the cranium at the age 5 months, moulding helmet therapy is a possible treatment option.
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