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[Patient with relapsed hyperparathyroidism and neck swelling]
Ian F Faneyte1, Rieneke E Sanson, Susan van Eeden
1Academisch Medisch Centrum/Universiteit van Amsterdam, Afd. Chirurgie, Amsterdam, The Netherlands.
Nederlands Tijdschrift Voor Geneeskunde
|October 28, 2009
Summary
Parathyromatosis, a rare disorder of ectopic parathyroid tissue, presented as a neck mass in a patient with prior hyperparathyroidism. Surgical resection is the primary treatment for this non-malignant condition.
Area of Science:
- Endocrinology
- Surgical Pathology
Background:
- Primary hyperparathyroidism history and prior surgery.
- Development of a growing neck mass over months.
Observation:
- Physical exam revealed a 3 cm solid, elastic, non-fixed neck swelling.
- Imaging (MRI) suggested parathyroid carcinoma.
- Neck examination showed a lobed tumor with yellowish-brown deposits.
Findings:
- Histology ruled out malignancy.
- Diagnosis confirmed as parathyromatosis, a rare disorder of hormonally active ectopic parathyroid tissue.
Implications:
- Parathyromatosis requires surgical management for radical resection.
- Calcimimetic agents may serve as adjuvant therapy.
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