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Updated: Jun 19, 2026

Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome
06:39

Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome

Published on: October 3, 2018

How to treat MDS without stem cell transplantation

Norbert Gattermann1

  • 1Klinik für Hämatologie, Onkologie u. klinische Immunology Heinrich-Heine-Universität Moorenstr. 5D-40225 Düsseldorf, Germany. gattermann@med.uni-duesseldorf.de

Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
|October 28, 2009
PubMed

Although allogeneic hematopoietic cell transplantation (HCT) is the only proven curative treatment for myelodysplastic syndromes (MDS), it is only used to treat a minority of MDS patients. The majority of patients are too old or suffer from comorbidities rendering allogeneic HCT too risky. Alternative treatment strategies for patients with higher risk MDS try to alter the natural course of disease by preventing or delaying leukemic transformation. In patients with lower risk MDS, treatment is mainly focused on maintaining or improving the quality of life.

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