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Updated: Jun 19, 2026
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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
Cardiac segmental analysis in left ventricular noncompaction: experience in a pediatric population
Rajesh Punn1, Norman H Silverman
1Stanford University, Lucile Packard Children's Hospital, Palo Alto, California, USA.
Summary
Left ventricular noncompaction (LVNC) in children is worse with more segments involved, leading to poorer outcomes. Congenital heart disease also worsens prognosis in pediatric LVNC patients.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Echocardiography
Background:
- Echocardiography is a diagnostic tool for left ventricular noncompaction (LVNC).
- Previous studies have not utilized the 16-segment model for pediatric LVNC.
- Congenital heart disease is often associated with pediatric LVNC.
Purpose of the Study:
- To investigate LVNC in children using the 16-segment model.
- To correlate LVNC severity with patient outcomes.
- To assess the impact of congenital heart disease on pediatric LVNC prognosis.
Main Methods:
- Retrospective analysis of 44 pediatric LVNC patients.
- Application of the 16-segment model to assess noncompaction/compaction ratio.
- Measurement of shortening and ejection fractions.
Main Results:
- LVNC incidence was 0.3% in pediatric admissions.
- Patients with worse outcomes (death/transplant) had more congenital heart disease (50% vs 18%).
- Increased segments involved, lower shortening (16% vs 29%), and ejection fractions (24% vs 47%) correlated with poorer outcomes.
Conclusions:
- In pediatric LVNC, more involved segments predict poor outcomes like low ejection fraction, death, or transplant.
- Pediatric LVNC with associated congenital heart disease has a worse prognosis than in adults.
