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Published on: March 14, 2011
Influence of Magnolol on the bystander effect induced by alpha-particle irradiation
T P W Wong1, Y L Law, A K W Tse
1Department of Physics and Materials Science, City University of Hong Kong, Kowloon Tong, Hong Kong.
Abstract:
In this work, the influence of Magnolol on the bystander effect in alpha-particle irradiated Chinese hamster ovary (CHO) cells was examined. The bystander effect was studied through medium transfer experiments. Cytokinesis-block micronucleus (CBMN) assay was performed to quantify the chromosome damage induced by alpha-particle irradiation. Our results showed that the alpha-particle induced micronuclei (MN) frequencies were suppressed with the presence of Magnolol.
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