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Endoscopic duodenal biopsy in children
Mohammad Issa El Mouzan1, Asaad Mohammad Abdullah Assiri, Abdullah Suleiman Al Herbish
1Department of Pediatrics, College of Medicine and KKUH, King Saud University, Riyadh, Saudi Arabia. drmouzan@gmail.com
Summary
Endoscopic duodenal biopsy (EDB) is effective for diagnosing villous atrophy and other pediatric gastroenteropathies. This procedure is recommended for both developed and developing countries when resources permit.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Endoscopy
- Histopathology
Background:
- Small bowel biopsy is crucial for diagnosing gastrointestinal conditions.
- Endoscopic forceps biopsy is preferred over suction capsules, but data from developing nations are limited.
Purpose of the Study:
- To evaluate the diagnostic utility of endoscopic duodenal biopsies (EDB) in children within a specific community.
- To assess the effectiveness of EDB in a developing country context.
Main Methods:
- Retrospective analysis of 241 endoscopic duodenal biopsies performed on pediatric patients (under 18 years) between 1993 and 2002.
- Data collected included patient demographics, biopsy indications, endoscopic findings, and histopathology results.
Main Results:
- Common indications for EDB were short stature (48%) and chronic diarrhea (43%).
- Villous atrophy was prevalent in children with chronic diarrhea (40%) and short stature (22%).
- EDB identified other conditions including Giardia lamblia, lymphangiectasis, and Mycobacterium avium intracellulare.
Conclusions:
- Endoscopic duodenal biopsy is a valuable tool for diagnosing villous atrophy and various other pediatric gastroenteropathies.
- EDB is a suitable and recommended procedure for both industrialized and developing countries, provided adequate expertise and equipment are available.
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