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Expanding criteria for peritoneal dialysis use
1Department of Nephrology, Universitary Hospital Marqués de Valdecilla, Santander, Spain. nefpfm@humv.es
Peritoneal dialysis (PD) offers social, clinical, and economic benefits for end-stage renal disease patients but remains underutilized. This review examines PD
Area of Science:
- Nephrology
- Renal Replacement Therapy
- Public Health
Background:
- Growing global population with end-stage renal disease (ESRD) requires renal replacement therapy.
- Home-based dialysis, particularly peritoneal dialysis (PD), is identified as the most cost-effective treatment option.
- Despite numerous advantages, PD is significantly underutilized as a renal replacement therapy.
Purpose of the Study:
- To review the current status of peritoneal dialysis (PD) utilization worldwide.
- To analyze the costs, complications, and potential improvements associated with PD.
- To understand factors contributing to the low incidence and prevalence of PD.
Main Methods:
- Systematic literature review of peritoneal dialysis (PD) prevalence and incidence.
- Analysis of economic data comparing PD with other renal replacement therapies.
- Review of clinical outcomes and complication rates associated with PD.
- Exploration of policy and healthcare system changes aimed at increasing PD use.
Main Results:
- Peritoneal dialysis (PD) demonstrates significant cost advantages over other renal replacement therapies.
- Despite clinical and economic benefits, PD incidence and prevalence remain low globally.
- Various factors contribute to the underutilization of PD, including healthcare system structures and patient/physician perceptions.
Conclusions:
- Peritoneal dialysis (PD) is an underutilized but cost-effective renal replacement therapy with significant advantages.
- Addressing barriers and implementing strategies to enhance PD use is crucial for managing the growing ESRD population.
- Further research and policy interventions are needed to increase the adoption of PD worldwide.
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Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...

