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Characterisation of oxidized recombinant human galectin-1

Stacy A Scott1, Andrea Bugarcic, Helen Blanchard

  • 1Institute for Glycomics, Gold Coast Campus, Griffith University, Queensland 4222, Australia.

Protein and Peptide Letters
|October 29, 2009
PubMed
Summary

Oxidized human galectin-1, implicated in immune responses and tumor development, was produced in milligram quantities. Biophysical studies revealed distinct oxidized forms with altered shapes and lost lectin activity, yielding a stable species for structural analysis.

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