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Related Experiment Video

Updated: Jun 19, 2026

Doppler Optical Coherence Tomography of Retinal Circulation
10:46

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

Ocular blood flow assessment using continuous laser Doppler flowmetry.

Charles E Riva1, Martial Geiser, Benno L Petrig

  • 1Department of Ophthalmology (Dir. Prof. Emilio Campos), University of Bologna, Italy. charles.riva@netplus.ch

Acta Ophthalmologica
|October 29, 2009
PubMed
Summary

Continuous laser Doppler flowmetry (LDF) measures red blood cell flux in ocular tissues. Further research is needed to fully utilize LDF for assessing microcirculatory hemodynamics.

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Physiology

Background:

  • Laser Doppler flowmetry (LDF) is a non-invasive technique.
  • Assessing microcirculatory hemodynamics is crucial in ophthalmology.
  • Ocular blood flow measurements are vital for understanding various eye conditions.

Purpose of the Study:

  • To describe the application of continuous laser Doppler flowmetry (LDF) for measuring red blood cell flux.
  • To detail the physical principles, devices, and clinical protocols for LDF in ocular tissues.
  • To discuss the parameters, calibration, reproducibility, and limitations of LDF in ophthalmology.

Main Methods:

  • Continuous laser Doppler flowmetry (LDF).
  • Measurement of red blood cell flux in the optic nerve head, iris, and subfoveal choroid.

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Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry
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Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry

Published on: January 19, 2020

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Last Updated: Jun 19, 2026

Doppler Optical Coherence Tomography of Retinal Circulation
10:46

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry
07:12

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry

Published on: January 19, 2020

  • Review of LDF devices, clinical protocols, and calibration procedures.

    • Main Results:

    • LDF technique successfully applied to measure red blood cell flux in key ocular vascular beds.
    • Detailed exposition of LDF principles, instrumentation, and methodologies provided.
    • Discussion on parameters, calibration, reproducibility, and limitations of the LDF technique.

    Conclusions:

    • Continuous LDF is a valuable tool for assessing ocular microcirculatory hemodynamics.
    • Further research is required to overcome existing limitations and maximize LDF's potential.
    • LDF offers promising applications in diagnosing and managing ophthalmic diseases related to blood flow.