Related Experiment Video
Updated: Jun 19, 2026

10:26
Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology
Published on: August 18, 2023
Rabies in foxes, Aegean region, Turkey
Ad Vos1, Conrad Freuling, Seza Eskiizmirliler
1IDT Biologika GmbH, Dessau-Rosslau, Germany. ad.vos@idt-biologika.de
Emerging Infectious Diseases
|October 29, 2009
Summary
Rabies spread rapidly among foxes in Turkey during the late 1990s, likely from dogs, increasing cattle cases. Oral fox vaccination was implemented to control this wildlife rabies outbreak.
Area of Science:
- Veterinary Medicine
- Epidemiology
- Wildlife Disease Control
Background:
- Rabies outbreak in the Aegean region of Turkey during the late 1990s.
- Rapid spread of rabies among the fox population.
- Likely spillover from domestic dogs to wildlife, impacting cattle.
Purpose of the Study:
- To investigate the epidemiology of a fox rabies outbreak in Turkey.
- To evaluate the impact of canine rabies on cattle.
- To assess the implementation of oral rabies vaccination (ORV) in foxes for disease control.
Main Methods:
- Surveillance of rabies cases in foxes and cattle.
- Investigation of potential transmission routes from dogs to foxes.
- Deployment of oral rabies vaccination programs targeting the fox population.
Main Results:
- Significant increase in rabies incidence in foxes.
- Documented cases of rabies in cattle linked to the fox outbreak.
- Successful implementation of oral fox vaccination strategies.
Conclusions:
- Foxes played a key role in the transmission dynamics of the rabies outbreak.
- Oral rabies vaccination is a viable strategy for controlling wildlife rabies.
- Interventions targeting wildlife reservoirs are crucial for protecting livestock.
Related Concept Videos
Rabies
Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Toxoplasmosis
Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
Arboviral Encephalitis
Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.

