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Poor clinical sensitivity of rapid antigen test for influenza A pandemic (H1N1) 2009 virus

Jan Felix Drexler1, Angelika Helmer, Heike Kirberg

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Emerging Infectious Diseases
|October 29, 2009
PubMed

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Influenza

Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...