Seasonal pattern of pneumonia mortality among under-five children in Nairobi's informal settlements

Yazoume Ye1, Eliya Zulu, Maurice Mutisya

  • 1African Population and Health Research CenterAPHRC, Nairobi, Kenya. yyazoume@aphrc.org

Insights

Pneumonia is the leading cause of death for children under five in Nairobi

Area of Science:

  • Public Health
  • Epidemiology
  • Pediatrics

Background:

  • Pneumonia poses a significant threat to children under five globally.
  • Understanding seasonal variations in pneumonia mortality is crucial for targeted interventions.
  • Nairobi's urban slums present unique demographic and environmental factors influencing child mortality.

Purpose of the Study:

  • To investigate the seasonal patterns of pneumonia mortality in under-five children residing in Nairobi's slums.
  • To identify specific periods of increased pneumonia risk to inform public health strategies.

Main Methods:

  • Utilized longitudinal data from the Nairobi Urban and Demographic Surveillance System (NUHDSS) (2003-2005).
  • Included 17,787 children under five, analyzing 436 deaths, with verbal autopsy for 377.
  • Employed Poisson regression to model quarterly pneumonia mortality risk.

Main Results:

  • Pneumonia accounted for 25.7% of all under-five deaths.
  • Pneumonia mortality risk was significantly higher in the second quarter (April-June) (RR=2.3, CI: 1.2-4.2) compared to the fourth quarter.
  • The highest risk period coincided with the rainy and early cold seasons.

Conclusions:

  • Pneumonia-related mortality among under-five children in Nairobi's slums exhibits a distinct seasonal pattern.
  • Increased pneumonia mortality risk is associated with the rainy and early cold seasons (April-June).
  • Findings support the need for seasonal public health interventions targeting pneumonia in this vulnerable population.

Related Concept Videos

Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps: