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Published on: February 23, 2014
Seasonal pattern of pneumonia mortality among under-five children in Nairobi's informal settlements
Yazoume Ye1, Eliya Zulu, Maurice Mutisya
1African Population and Health Research CenterAPHRC, Nairobi, Kenya. yyazoume@aphrc.org
Insights
Pneumonia is the leading cause of death for children under five in Nairobi
Area of Science:
- Public Health
- Epidemiology
- Pediatrics
Background:
- Pneumonia poses a significant threat to children under five globally.
- Understanding seasonal variations in pneumonia mortality is crucial for targeted interventions.
- Nairobi's urban slums present unique demographic and environmental factors influencing child mortality.
Purpose of the Study:
- To investigate the seasonal patterns of pneumonia mortality in under-five children residing in Nairobi's slums.
- To identify specific periods of increased pneumonia risk to inform public health strategies.
Main Methods:
- Utilized longitudinal data from the Nairobi Urban and Demographic Surveillance System (NUHDSS) (2003-2005).
- Included 17,787 children under five, analyzing 436 deaths, with verbal autopsy for 377.
- Employed Poisson regression to model quarterly pneumonia mortality risk.
Main Results:
- Pneumonia accounted for 25.7% of all under-five deaths.
- Pneumonia mortality risk was significantly higher in the second quarter (April-June) (RR=2.3, CI: 1.2-4.2) compared to the fourth quarter.
- The highest risk period coincided with the rainy and early cold seasons.
Conclusions:
- Pneumonia-related mortality among under-five children in Nairobi's slums exhibits a distinct seasonal pattern.
- Increased pneumonia mortality risk is associated with the rainy and early cold seasons (April-June).
- Findings support the need for seasonal public health interventions targeting pneumonia in this vulnerable population.
Abstract:
Using longitudinal data from the Nairobi Urban and Demographic Surveillance System (NUHDSS), we examined the seasonal pattern of pneumonia mortality among under-five children living in Nairobi's slums. We included 17,787 under-five children resident in the NUHDSS from January 1, 2003 to December 31, 2005 in the analysis. Four hundred thirty-six deaths were observed and cause of death was ascertained by verbal autopsy for 377 of these deaths. Using Poisson regression, we modeled the quarterly mortality risk for pneumonia. The overall person-years (PYs) were 21,804 giving a mortality rate of 20.1 per 1,000 PYs in the study population. Pneumonia was the leading cause of death contributing 25.7% of the total deaths. Pneumonia mortality was highest in the second quarter (risk ratio [RR] = 2.3, confidence interval [CI]: 1.2-4.2 compared with the fourth quarter). The study provides evidence that pneumonia-related mortality among under-fives in Nairobi's slums is higher from April to June corresponding to the rainy season and the beginning of the cold season.
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