Related Experiment Video
Updated: Jun 19, 2026

08:41
Modeling Chemotherapy Resistant Leukemia In Vitro
Published on: February 9, 2016
The road to cancer control goes through leukemia research
1The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 55, Houston, TX 77030 USA. efreirei@mdanderson.org
Current Oncology (Toronto, Ont.)
|October 29, 2009
Abstract
No abstract available in PubMed .
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When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
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When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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