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Infant anaplastic large cell lymphoma with hemophagocytic syndrome
Tze S Khor1, Angela J Alessandri, Gareth P Jevon
1Princess Margaret Hospital and PathWest, Roberts Road, Subiaco, Western Australia 6008, Australia. tzesk@member.rcpa.edu.au
Abstract:
Anaplastic large cell lymphoma (ALCL), anaplastic lymphoma kinase (ALK)-positive, is uncommon in infancy. We present an unusual occurrence of infant ALCL, ALK-positive, associated with hemophagocytic syndrome. To the best of our knowledge, there have been no cases of infant ALCL, ALK-positive, described that have been associated with hemophagocytic syndrome. Particularly in this age group, primary hemophagocytic syndrome is also a consideration, which raises particular differential diagnostic considerations.