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Esophageal candidiasis among a dyspeptic population
I A Al Mofleh1, M A Al Mofarreh
1Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Summary
Esophageal candidiasis is common in patients with dyspepsia, often presenting with atypical symptoms. Treatment with oral nystatin and addressing underlying conditions effectively resolves symptoms.
Area of Science:
- Gastroenterology
- Mycology
Background:
- Esophageal candidiasis (EC) is an opportunistic infection.
- Dyspeptic patients may present with undiagnosed EC.
Purpose of the Study:
- To investigate the prevalence and clinical presentation of EC in dyspeptic patients.
- To evaluate the efficacy of oral nystatin treatment for EC.
Main Methods:
- Retrospective analysis of 59 patients diagnosed with EC via endoscopy and cytology.
- Review of patient demographics, symptoms, endoscopic findings, and treatment outcomes.
Main Results:
- Median age was 46.38 years; 51% had no precipitating factors.
- Only 30% presented with typical symptoms; distal esophagus involvement was common.
- Scattered thrush observed in 97% of cases; confirmed by cytology.
- Oral nystatin and treatment of associated conditions led to symptom improvement in all 46 followed patients.
Conclusions:
- Esophageal candidiasis is a frequent finding in the dyspeptic population.
- Atypical symptoms are more common than typical ones in EC.
- Oral nystatin is an effective treatment for EC, especially when combined with management of underlying conditions.
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