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Related Concept Videos

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Clinical Manifestations:

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Related Experiment Video

Updated: Jun 19, 2026

In Vitro Apical-Out Enteroid Model of Necrotizing Enterocolitis
09:11

In Vitro Apical-Out Enteroid Model of Necrotizing Enterocolitis

Published on: June 8, 2022

Necrotizing enterocolitis, surgical experience.

M M Saleem1, Z Skef, O Bashir

  • 1Department of Surgery, Security Forces Hospital, Riyadh, Saudi Arabia.

Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association
|October 30, 2009
PubMed
Summary
This summary is machine-generated.

Surgical management for necrotizing enterocolitis (NEC) in neonates yielded a 72% survival rate. Pneumoperitoneum was the primary surgical indication, with bowel resection and enterostomy being the most common procedure.

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Last Updated: Jun 19, 2026

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09:11

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Published on: June 8, 2022

Microfluidic Model of Necrotizing Enterocolitis Incorporating Human Neonatal Intestinal Enteroids and a Dysbiotic Microbiome
06:51

Microfluidic Model of Necrotizing Enterocolitis Incorporating Human Neonatal Intestinal Enteroids and a Dysbiotic Microbiome

Published on: July 28, 2023

A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis
08:42

A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis

Published on: April 10, 2019

Area of Science:

  • Neonatal surgery
  • Pediatric gastroenterology
  • Surgical outcomes

Background:

  • Necrotizing enterocolitis (NEC) is a critical gastrointestinal emergency in neonates.
  • Surgical intervention is often required for severe or refractory NEC cases.

Purpose of the Study:

  • To analyze surgical management strategies and outcomes for necrotizing enterocolitis.
  • To identify common indications for surgery and surgical procedures in NEC.

Main Methods:

  • Retrospective review of 29 neonates undergoing surgical management for NEC between 1988 and 1994.
  • Data collected included gestational age, birth weight, age at NEC onset, surgical indications, procedures, and survival rates.

Main Results:

  • The study included 15 males and 14 females, with an average gestational age of 32.7 weeks and average birth weight of 1,680 grams.
  • Pneumoperitoneum (55%) was the most frequent indication for surgery, followed by medical treatment failure.
  • The most common surgical procedure was bowel resection with enterostomy (50%), achieving an overall survival rate of 72%.

Conclusions:

  • Surgical management of NEC, particularly bowel resection with enterostomy, can achieve significant survival rates in neonates.
  • Early recognition and timely surgical intervention are crucial for improving outcomes in necrotizing enterocolitis.