Presenting manifestations of eosinophilic cystitis in two Filipino children

Paul Joseph T Galutira1, Beatrice B Canonigo, Ma Rosario F Cabansag

  • 1Section of Pediatric Nephrology, University of Santo Tomas Hospital, Manila, Philippines. pj_7611@yahoo.com

Insights

Eosinophilic cystitis, a rare pediatric condition, presents with urinary issues and blood. Treatment with corticosteroids led to symptom resolution in two Filipino children.

Area of Science:

  • Pediatric Urology
  • Nephrology
  • Pathology

Background:

  • Eosinophilic cystitis is an extremely rare condition in children.
  • It is characterized by eosinophilic infiltration of the bladder wall.

Observation:

  • Two Filipino children presented with irritative voiding symptoms, gross hematuria, and peripheral eosinophilia.
  • Imaging revealed hydroureteronephrosis and bladder wall thickening.
  • Diagnosis was confirmed via cystoscopy and transurethral biopsy.

Findings:

  • Both patients received corticosteroid therapy, with one also receiving an antihistamine.
  • Complete resolution of signs and symptoms was observed in both cases.
  • Follow-up imaging showed normalization of hydroureteronephrosis and bladder wall thickness.

Implications:

  • Corticosteroids appear effective in treating pediatric eosinophilic cystitis.
  • Early diagnosis and prompt treatment can lead to favorable outcomes.
  • This case report highlights the importance of considering rare diagnoses in pediatric urological conditions.

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