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Purification of intact microtubules from brain

J B Kirkpatrick1, L Hyams, V L Thomas

  • 1Department of Pharmacology, Rutgers Medical School, New Brunswick, New Jersey 08903.

The Journal of Cell Biology
|October 30, 2009
PubMed

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Microtubules01:35

Microtubules

There are three types of cytoskeletal structures in eukaryotic cells—microfilaments, intermediate filaments, and microtubules. With a diameter of about 25 nm, microtubules are the thickest of these fibers. Microtubules carry out a variety of functions that include cell structure and support, transport of organelles, cell motility (movement), and the separation of chromosomes during cell division.Microtubules are hollow tubes whose walls are made up of globular tubulin proteins. Each tubulin...