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Related Experiment Video

Updated: Jun 19, 2026

Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation
06:47

Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation

Published on: January 28, 2021

EXPERIMENTAL LIPEMIA IN RABBITS.

T R Boggs1, R S Morris

  • 1Clinical Laboratory of the Johns Hopkins Hospital and University.

The Journal of Experimental Medicine
|October 30, 2009
PubMed
Summary

This study reports a novel observation of lipemia (fat in the blood) associated with simple hemorrhage in rabbits, suggesting a potential link to human anemias. Further research is needed to understand the underlying mechanisms of this fat metabolism disorder.

Area of Science:

  • Biochemistry
  • Hematology
  • Pathology

Background:

  • Literature review revealed no prior descriptions of lipemia linked to simple hemorrhage.
  • High blood fat percentages are documented in diabetic patients, with varying fat compositions.
  • Previous studies induced alimentary lipemia in animals through specific diets.

Purpose of the Study:

  • To document and investigate a newly observed phenomenon of lipemia in relation to hemorrhage.
  • To explore the potential occurrence of lipemia in human anemias by analogy.
  • To characterize the chemical properties of the observed lipemic fat.

Main Methods:

  • Observation of lipemia in rabbits following induced hemorrhage.
  • Chemical analysis of the lipemic blood serum, including fat insolubility and "constants."

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Related Experiment Videos

Last Updated: Jun 19, 2026

Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation
06:47

Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation

Published on: January 28, 2021

Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits
07:34

Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits

Published on: June 2, 2019

An Experimental Model of Diet-Induced Metabolic Syndrome in Rabbit: Methodological Considerations, Development, and Assessment
10:31

An Experimental Model of Diet-Induced Metabolic Syndrome in Rabbit: Methodological Considerations, Development, and Assessment

Published on: April 20, 2018

  • Investigation of the effect of calcium precipitation on serum fat composition.

    • Main Results:

    • A moderate lipemia was observed in a case of secondary anemia due to hemorrhoids.
    • The fat composition in lipemic rabbits differed from previously described fats, notably in insolubility.
    • Decalcification of serum appeared to decompose a potential protein-calcium-lecithin fat complex.

    Conclusions:

    • The study presents a novel association between simple hemorrhage and lipemia.
    • Findings suggest a potential analogy for lipemia in human anemias, warranting further investigation.
    • The mechanism may involve abnormal fat metabolism possibly influenced by tissue protein loss or reduced oxidation.